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09-069 Anti-ATF6 Antibody

Detect ATF6 using this Anti-ATF6 Antibody validated for use in WB.

Anti-ATF6 Antibody: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Research Category: Signaling, Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: ATF6, activating transcription factor 6 UniProt Number: P18850
09-069
100 µL  
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Tabella delle specifiche principali

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number09-069
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-ATF6 Antibody
Background InformationATF6 (Activating Transcription Factor 6, Cyclic AMP-dependent transcription factor ATF6) is a stress activated leucine zipper transcription factor involved in activating transcription of endoplasmic reticulum (ER) molecules in response to accumulation of unfolded proteins in the ER. ATF6 is originally a 90 kDa type II transmembrane glycoprotein that is converted to a 50 kDa soluble nuclear form, retaining its N-terminal domain, including the leucine zipper. Unfolded protein accumulation in the ER results in the cleavage of ATF6 to release its cytoplasmic domain that then enters the nucleus. ATF6 binds to an element designated ER Stress Response Element (ERSA) that appears in the promoter of glucose-regulated proteins (GRPs) such as GRP78, GPR94, and calreticulin.
References
Product Information
FormatAffinity Purified
PresentationAffinity purified rabbit polyclonal IgG in storage buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect ATF6 using this Anti-ATF6 Antibody validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-tagged synthestic peptide synthesized to the N-terminal region of human ATF6 designated as the Cytoplasmic Domain.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ATF6
  • activating transcription factor 6
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight90 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by western blot on HeLa lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -20°C
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
09-069 04053252470967