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164606 Aminopeptidase N/CD13 Inhibitor - Calbiochem

The Aminopeptidase N/CD13 Inhibitor controls the biological activity of Aminopeptidase N/CD13. This small molecule/inhibitor is primarily used for Neuroscience applications.

Aminopeptidase N/CD13 Inhibitor - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 4-tert-butylphenyl hydrogen 1-aminopropylphosphonate

164606
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₁₃H₂₂NO₃P

Products

Numero di catalogoConfezionamento Qtà/conf
164606-10MG Bottiglia di vetro 10 mg
Description
OverviewAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
Catalogue Number164606
Brand Family Calbiochem®
Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
References
ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
Product Information
FormWhite solid
Hill FormulaC₁₃H₂₂NO₃P
Chemical formulaC₁₃H₂₂NO₃P
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
164606-10MG 04055977207613

Documentation

Aminopeptidase N/CD13 Inhibitor - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Aminopeptidase N/CD13 Inhibitor - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
164606

Riferimenti bibliografici

Panoramica delle referenze
Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-April-2012 JSW
Synonyms4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
DescriptionAn alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC50=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
FormWhite solid
Chemical formulaC₁₃H₂₂NO₃P
Structure formulaStructure formula
Purity≥95% by HPLC
Solubility0.1N NaOH (1 mg/ml). Only partially soluble at 1 mg/ml in DMSO or H₂O.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGrzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.