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116814 Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem

A cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 µM).

Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Adenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V

Primary Target: PKA
116814
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
151837-09-1C₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH

Products

Numero di catalogoConfezionamento Qtà/conf
116814-5UMOL Bottiglia di vetro 5 umol
Description
OverviewA cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 µM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.
Note: 5 µmol = 2.23 mg.
Catalogue Number116814
Brand Family Calbiochem®
SynonymsAdenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V
References
ReferencesKaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
Butt, E., et al. 1990. FEBS Lett. 263, 47.
Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
Rothermel, J.D. 1988. Biochem. J. 251, 757.
Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.
Product Information
CAS number151837-09-1
ATP CompetitiveN
FormCrystalline solid
Hill FormulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
Chemical formulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKA
Primary Target K<sub>i</sub>11 µM against protein kinase A
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
116814-5UMOL 07790788047825

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
116814

Riferimenti bibliografici

Panoramica delle referenze
Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
Butt, E., et al. 1990. FEBS Lett. 263, 47.
Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
Rothermel, J.D. 1988. Biochem. J. 251, 757.
Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.

Brochure

Titolo
Inhibitor Sourcebook 3rd Edition
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2007 RFH
SynonymsAdenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V
DescriptionCell permeable inhibitor of protein kinase A (Ki = 11 µM). Resistant to hydrolysis by phosphodiesterases. Note: 5 µmol = 2.23 mg
FormCrystalline solid
CAS number151837-09-1
Chemical formulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (20 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
Butt, E., et al. 1990. FEBS Lett. 263, 47.
Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
Rothermel, J.D. 1988. Biochem. J. 251, 757.
Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.