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538927 15d-PGJ₂ - CAS 87893-55-8 - Calbiochem

538927
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
87893-55-8C₂₀H₂₈O₃

Products

Numero di catalogoConfezionamento Qtà/conf
538927-1MG Fiala di plastica 1 mg
Description
OverviewA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding. Down-regulates inducible nitric oxide synthase (iNOS).
Catalogue Number538927
Brand Family Calbiochem®
SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
References
ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.
Product Information
CAS number87893-55-8
ATP CompetitiveN
FormOil
Hill FormulaC₂₀H₂₈O₃
Chemical formulaC₂₀H₂₈O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA natural ligand for PPARγ-dependent adipogenesis
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
538927-1MG 04055977195279

Documentation

15d-PGJ₂ - CAS 87893-55-8 - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

15d-PGJ₂ - CAS 87893-55-8 - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
538927

Riferimenti bibliografici

Panoramica delle referenze
Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.

Brochure

Titolo
Bioactive Lipids Technical Bulletin
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-July-2016 JSW
SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
DescriptionA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.
FormOil
Intert gas (Yes/No) Packaged under inert gas
CAS number87893-55-8
Chemical formulaC₂₀H₂₈O₃
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.