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251700 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 1,5-DNS-GGACK, 2HCl

Primary Target: UPA
251700
Purchase on Sigma-Aldrich

Panoramica

Replacement Information

Products

Numero di catalogoConfezionamento Qtà/conf
251700-5MG Fiala di plastica 5 mg
Description
OverviewEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
Catalogue Number251700
Brand Family Calbiochem®
Synonyms1,5-DNS-GGACK, 2HCl
References
ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Product Information
ATP CompetitiveN
FormOff-white solid
ReversibleN
Quality LevelMQ100
Applications
Application1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.
Biological Information
Primary TargetUPA
Primary Target IC<sub>50</sub>100 nM for factor Xa
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Numero di catalogo GTIN
251700-5MG 04055977217957

Documentation

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem MSDS

Titolo

Scheda di sicurezza (MSDS) 

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem Certificati d'Analisi

TitoloNumero di lotto
251700

Riferimenti bibliografici

Panoramica delle referenze
Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Scheda tecnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-June-2008 RFH
Synonyms1,5-DNS-GGACK, 2HCl
DescriptionEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
FormOff-white solid
SolubilityReconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.
Storage Protect from moisture
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Toxicity Standard Handling
ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.