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251010 1-β-D-Arabinofuranosylcytosine - CAS 147-94-4 - Calbiochem

Anticancer, antiviral agent that is especially effective against leukemias.

1-β-D-Arabinofuranosylcytosine - CAS 147-94-4 - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Ara-C, Cytarabine, Cytosine Arabinoside

Primary Target: Anticancer, antiviral agent that is especially effective against leukemias
251010
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Tabella delle specifiche principali

CAS #Empirical Formula
147-94-4C₉H₁₃N₃O₅

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Description
OverviewAnticancer, antiviral agent that is especially effective against leukemias. Induces apoptosis in human myeloid leukemia cells and in rat sympathetic neurons. Induces G1/S phase cell cycle arrest.
Catalogue Number251010
Brand Family Calbiochem®
SynonymsAra-C, Cytarabine, Cytosine Arabinoside
References
ReferencesZarilli, R., et al. 1999. Gastroenterology 116, 1358.
Dessi, F., et al. 1995. J. Neurochem. 64, 1980.
Grant, S., et al. 1994. Oncol. Res. 6, 87.
Greenberg, A.L., et al. 1994. Cancer 74, 1261.
Perrino, F.W., et al. 1997. J. Biol. Chem. 269, 16357.
Tomkins, C.E., et al. 1994. J. Cell Sci. 107, 1499.
Taddie, J.A., and Traktman, P. 1993. J. Virol. 67, 4323.
Brach, M.A., et al. 1992. Mol. Pharmacol. 41, 60.
Este, E., et al. 1992. Blood 79, 2246.
Owens, J.K., et al. 1992. Cancer Res. 52, 2389.
Product Information
CAS number147-94-4
ATP CompetitiveN
FormWhite solid
Hill FormulaC₉H₁₃N₃O₅
Chemical formulaC₉H₁₃N₃O₅
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetAnticancer, antiviral agent that is especially effective against leukemias
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSHA5425000
Safety Information
R PhraseR: 20/21/22-36/37/38-43-61

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
May cause sensitization by skin contact.
May cause harm to the unborn child.
S PhraseS: 22-36-45

Do not breathe dust.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Global Trade Item Number
Numero di catalogo GTIN
251010-1GM 04055977199192