Millipore Sigma Vibrant Logo

610225 Tigecycline - CAS 220620-09-7 - Calbiochem

A broad-spectrum glyclcycline class of antimicrobial agent that is active against both Gram positive and Gram negative bacteria.

Tigecycline - CAS 220620-09-7 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 9-t-Butylglycylamido-minocycline

View Products on Sigmaaldrich.com
610225
  
Prix en cours de récupération
Le prix n'a pas pu être récupéré
La quantité minimale doit être un multiple de
Maximum Quantity is
À la validation de la commande Plus d'informations
Vous avez sauvegardé ()
 
—
Demander le prix
—
Disponibilité limitée Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

       

      Contacter le Service Clients

      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      220620-09-7C₂₉H₃₉N₅O₈
      Description
      OverviewA broad-spectrum glyclcycline class of antimicrobial agent that is active against both Gram positive and Gram negative bacteria. Exhibits toxicity for human AML cells at all stages of development in both in vitro and in vivo models. Selectively kills leukemic stem and progenitor cells (LD50 ~10 µM) and reduces the repopulating ability of the primary AML cells while sparing normal hematopoietic cells. Its action on growth and viability of eukaryotic cells is shown to be due to its inhibitory effects on mitochondrial protein translation and respiratory complex activity.
      Catalogue Number610225
      Brand Family Calbiochem®
      Synonyms9-t-Butylglycylamido-minocycline
      References
      ReferencesSkrtic, M., et al. 2011. Cancer Cell 20, 674.
      Olson, M.W., et al. 2006. Antimicrob. Agents Chemother. 50, 2156.
      Stein, G.E., and Craig, W.A., 2006. Clin. Infect Dis. 43, 518.
      Livermore, D.M., 2005. J. Antimicrob. Chemother. 56, 611.
      Product Information
      CAS number220620-09-7
      FormOrange powder
      Hill FormulaC₂₉H₃₉N₅O₈
      Chemical formulaC₂₉H₃₉N₅O₈
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36-60-61

      Irritating to eyes.
      May impair fertility.
      May cause harm to the unborn child.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      610225 0

      Documentation

      Tigecycline - CAS 220620-09-7 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Tigecycline - CAS 220620-09-7 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      610225

      Références bibliographiques

      Aperçu de la référence bibliographique
      Skrtic, M., et al. 2011. Cancer Cell 20, 674.
      Olson, M.W., et al. 2006. Antimicrob. Agents Chemother. 50, 2156.
      Stein, G.E., and Craig, W.A., 2006. Clin. Infect Dis. 43, 518.
      Livermore, D.M., 2005. J. Antimicrob. Chemother. 56, 611.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision09-July-2012 JSW
      Synonyms9-t-Butylglycylamido-minocycline
      DescriptionA broad-spectrum glyclcycline class of antimicrobial agent that is active against both Gram positive and Gram negative bacteria. Exhibits toxicity for human AML cells at all stages of development in both in vitro and in vivo models. Selectively kills leukemic stem and progenitor cells (LD50 ~10 µM) and reduces the repopulating ability of the primary AML cells while sparing normal hematopoietic cells. Its action on growth and viability of eukaryotic cells is shown to be due to its inhibitory effects on mitochondrial protein translation and respiratory complex activity.
      FormOrange powder
      Intert gas (Yes/No) Packaged under inert gas
      CAS number220620-09-7
      Chemical formulaC₂₉H₃₉N₅O₈
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Irritant
      ReferencesSkrtic, M., et al. 2011. Cancer Cell 20, 674.
      Olson, M.W., et al. 2006. Antimicrob. Agents Chemother. 50, 2156.
      Stein, G.E., and Craig, W.A., 2006. Clin. Infect Dis. 43, 518.
      Livermore, D.M., 2005. J. Antimicrob. Chemother. 56, 611.