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539572 Serine/Threonine Kinase Inhibitor Set - Calbiochem

The Serine/Threonine Kinase Inhibitor Set controls the biological activity of Serine/Threonine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Primary Target: PKA
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539572
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539572-1SET
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      Description
      OverviewA convenient set that offers several highly selective serine/threonine kinase inhibitors. Set contains 250 µg of protein kinase C inhibitor, Bisindolylmaleimide I (Cat. No. 203290); 1 mg of protein kinase A inhibitor, H-89, Dihydrochloride (Cat. No. 371963); 1 mg of PKG inhibitor, Protein Kinase G Inhibitor (Cat. No. 370654); 1 mg of MLCK inhibitor, ML-7 (Cat. No. 475880); 1 mg of CaM kinase II inhibitor, KN-93 (Cat. No. 422708); and 100 µg of the broad range Serine/Threonine Kinase inhibitor, Staurosporine (Cat. No. 569397). Supplied with a data sheet.
      Catalogue Number539572
      Brand Family Calbiochem®
      Application Data
      References
      ReferencesMartiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.
      Product Information
      FormSolid
      Hygroscopic Hygroscopic
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKA
      Secondary targetPKC, MLCK, Cam kinase II, PKG
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 23/25-36/37/38-45-63

      Toxic by inhalation and if swallowed.
      Irritating to eyes, respiratory system and skin.
      May cause cancer.
      Possible risk of harm to the unborn child.
      S PhraseS: 22-36/37/39-45-53

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Multiple Toxicity Values, refer to MSDS
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      539572-1SET 04055977194715

      Documentation

      Serine/Threonine Kinase Inhibitor Set - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Serine/Threonine Kinase Inhibitor Set - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      539572

      Références bibliographiques

      Aperçu de la référence bibliographique
      Martiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.

      Brochure

      Titre
      Protein Kinase Assay and Detection Kits Brochure
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-September-2007 JSW
      Application Data
      DescriptionA convenient set that offers several highly selective serine/threonine kinase inhibitors. Kinases play an important role in numerous signaling cascades. Highly selective protein kinase inhibitors are useful for dissecting these cascades to determine which specific kinases are involved in producing particular biological effects. The Serine/Threonine Kinase Inhibitor Set contains the following highly selective serine/ threonine kinase inhibitors in one convenient set:

      • Bisindolylmaleimide I (Cat. No. 203290), 250 µg
      • H-89, Dihydrochloride (Cat. No. 371963), 1 mg
      • KN-93 (Cat. No. 422708), 1 mg
      • ML-7 (Cat. No. 475880), 1 mg
      • Protein Kinase G Inhibitor (Cat. No. 370654), 1 mg
      • Staurosporine (Cat. No. 569397), 100 µg
      FormSolid
      SolubilityH₂O (1 mg/ml; Protein Kinase G Inhibitor)
      DMSO (1 mg/ml; all other inhibitors)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.
      Toxicity Multiple Toxicity Values, refer to MSDS
      ReferencesMartiny, G., et al. 1993. J. Biol. Chem. 268, 9194.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Chijiwa, T., et al. 1990. J. Biol. Chem. 265, 5267.
      Simu, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 968.
      Saitoh, M., et al. J. Biol. Chem. 262, 7796.
      Glass, D.B., et al. 1983. Biochem. J. 213, 159.
      Seynaeve, C.M., et al. 1994. Mol. Pharmacol. 45, 1207.
      Meyer, T., et al. 1989. Int. J. Cancer 43, 851.