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505626 (S)-Sulpiride - CAS 23672-07-3 - Calbiochem

(S)-Sulpiride - CAS 23672-07-3 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride

Primary Target: D2-like dopamine receptors
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      23672-07-3C₁₅H₂₃N₃O₄S
      Description
      Overview

      This product has been discontinued.



      Dopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
      Catalogue Number505626
      Brand Family Calbiochem®
      Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
      References
      ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
      Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
      Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
      Product Information
      CAS number23672-07-3
      FormWhite solid
      Hill FormulaC₁₅H₂₃N₃O₄S
      Chemical formulaC₁₅H₂₃N₃O₄S
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetD2-like dopamine receptors
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      505626 0

      Documentation

      (S)-Sulpiride - CAS 23672-07-3 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Eagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
      Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
      Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2013 JSW
      Synonyms(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl­-2-pyrrolidinyl)methyl]-2-methoxybenzamide, D2-like dopamine antagonist, (s)-Sulpiride, Sulpiride
      DescriptionDopamine D2 receptor antagonist with good aqueous solubility. S-sulpiride (200 nm) was used to confirm that dopamine currents were mediated through the D2 receptor in whole animal rat brain preps. IC50 of 0.01012 µM Antagonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis.
      FormWhite solid
      CAS number23672-07-3
      Chemical formulaC₁₅H₂₃N₃O₄S
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesEagle, D. M. et al. 2011. J. Neurosci. 31, 7349.
      Banala, A. K. et al. 2011. J. Med. Chem. 54, 3581.
      Seeman, P. and Van Tol, H. H. 1994. Trends Pharmacol. Sci. 15, 264.