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537009 Progranulin, CF, Mouse, Recombinant

Progranulin, CF, Mouse, Recombinant : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: PC cell-derived growth factor (PCDGF)

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      Aperçu

      Tableau de caractéristiques principal

      Purity
      ≥90% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.
      Catalogue Number537009
      Brand Family Calbiochem®
      SynonymsPC cell-derived growth factor (PCDGF)
      References
      ReferencesLiu, Y. et al. 2007. BMC Cancer 7, 22.
      Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
      Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
      Davidson, B. et al. 2004. Cancer 100, 2139.
      Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
      Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
      He, Z. et al. 2003. Nat. Med. 9, 225.
      He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
      Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
      Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
      Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
      Zhu, J. et al. 2002. Cell 111, 867.
      Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
      Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
      Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
      Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
      Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
      Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
      Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.
      Product Information
      FormLyophilized
      FormulationLyophilized from 0.2 µm filtered PBS.
      Quality LevelMQ100
      Biological Information
      Biological activitySignificantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
      Purity≥90% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1.0 EU/µg protein
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Global Trade Item Number
      Référence GTIN
      537009 0