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05-23-5501 Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem

N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism.

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05-23-5501
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
52232-67-4C₁₈₁H₂₉₁N₅₅O₅₁S₂

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      Description
      OverviewN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
      Catalogue Number05-23-5501
      Brand Family Calbiochem®
      References
      ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
      Dua, K., et al. 1994. Exp. Physiol. 79, 401.
      Product Information
      CAS number52232-67-4
      ATP CompetitiveN
      FormWhite to off-white lyophilized solid
      FormulationSupplied as an trifluoroacetate salt.
      Hill FormulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
      Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
      ReversibleN
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetHomeostatic control of Ca2+ and phosphate metabolism
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      05-23-5501-1MG 04055977226850

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Parathyroid Hormone 1-34, Human - CAS 52232-67-4 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      05-23-5501

      Références bibliographiques

      Aperçu de la référence bibliographique
      Matsui, H., et al. 1995. Am. J. Physiol. 268, R21.
      Dua, K., et al. 1994. Exp. Physiol. 79, 401.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision4-October-2018 JSW
      DescriptionN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
      FormWhite to off-white lyophilized solid
      FormulationSupplied as an trifluoroacetate salt.
      CAS number52232-67-4
      Chemical formulaC₁₈₁H₂₉₁N₅₅O₅₁S₂
      Peptide SequenceH-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
      Purity≥95% by HPLC
      Solubility5% acetic acid (1 mg/ml)
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 7034
      ReferencesMatsui, H., et al. 1995. Am. J. Physiol. 268, R21.
      Dua, K., et al. 1994. Exp. Physiol. 79, 401.

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      Catégories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Hormones > Other Hormones