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480014 NDSB-221

NDSB-221 : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 3-(1-Methylpiperidinium)-1-propane Sulfonate

480014
  
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      160788-56-7C₉H₁₉NO₃S
      Description
      Overview

      This product has been discontinued.





      A non-detergent sulfobetaine useful for the renaturation of unfolded proteins. At 1.8 M, NDSB-221 yields about 35% in native hen egg white lysozyme (HEWL), which is about 10-fold higher than in the absence of NDSB-221. At about 1.5 M, NDSB-221 efficiently increases the renaturation of β-D-galactosidase.
      Catalogue Number480014
      Brand Family Calbiochem®
      Synonyms3-(1-Methylpiperidinium)-1-propane Sulfonate
      References
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Product Information
      CAS number160788-56-7
      FormWhite solid
      Hill FormulaC₉H₁₉NO₃S
      Chemical formulaC₉H₁₉NO₃S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥95% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +15°C to +30°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      480014 0

      Documentation

      NDSB-221 Certificats d'analyse

      TitreNuméro de lot
      480014

      Références bibliographiques

      Aperçu de la référence bibliographique
      Goldberg, M.E., et al. 1996. Folding & Design 1, 21.

      Brochure

      Titre
      Biological Detergents Brochure
      Bulk Product Guide

      Citations

      Titre
    • Marina V. Backer, et al. (2005) Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature. Molecular Cancer Therapeutics 4, 1423-1429.
      		•
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      Synonyms3-(1-Methylpiperidinium)-1-propane Sulfonate
      DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, which are also sulfobetaines, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range. They prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. NDSB-221 at 1.8 M yields about 35% in native hen egg white lysozyme (HEWL), which is about 10-fold higher than in the absence of NDSB-221. At about 1.5 M, NDSB-221 efficiently increases the renaturation of β-D-galactosidase.
      FormWhite solid
      CAS number160788-56-7
      Chemical formulaC₉H₁₉NO₃S
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityH₂O (100 mg/ml)
      Storage +15°C to +30°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Toxicity Irritant
      ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
      Citation
    • Marina V. Backer, et al. (2005) Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature. Molecular Cancer Therapeutics 4, 1423-1429.
      		•

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      Catégories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines