Millipore Sigma Vibrant Logo

435800 Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem

Licochalcone-A, Synthetic, CAS 58749-22-7, is an estrogenic flavonoid with anti-tumor & antiparasitic properties. Reduces Bcl-2 expression and induces apoptosis in several human cancer cell lines.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

Primary Target: Anti-tumor and antiparasitic properties
View Products on Sigmaaldrich.com
435800
Voir les Prix & la Disponibilité

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
58749-22-7C₂₁H₂₂O₄

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
435800-10MG
Récupération des données relatives à la disponibilité...
—
Disponibilité limitée Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      		 Ampoule plast. 10 mg
      Prix en cours de récupération
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      —
      Demander le prix
      		 —
      435800-50MG
      Récupération des données relatives à la disponibilité...
      —
      Disponibilité limitée Disponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
        Pour le restant : Nous vous tiendrons informé
          Pour le restant : Nous vous tiendrons informé
          Nous vous tiendrons informé
          Contacter le Service Clients
          Contact Customer Service

          		 Ampoule plast. 50 mg
          Prix en cours de récupération
          Le prix n'a pas pu être récupéré
          La quantité minimale doit être un multiple de
          Maximum Quantity is
          À la validation de la commande Plus d'informations
          Vous avez sauvegardé ()
           
          —
          Demander le prix
          		 —
          Description
          OverviewAn estrogenic flavonoid with anti-tumor and antiparasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation, exhibits anti-tumor activity, and enhances the effect of Paclitaxel (Cat. No. 580555) and Vinblastine (Cat. No. 677175) chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
          Catalogue Number435800
          Brand Family Calbiochem®
          Synonyms(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
          References
          ReferencesRafi, M.M., et al. 2000. Anticancer Res. 20, 2653.
          Zhai, L., et al. 1999. J. Antimicrob. Chemother. 43, 793.
          Haraguchi, H., et al. 1998. Phytochemistry 48, 125.
          Park, E.J., et al. 1998. Planta Med. 64, 464.
          Chen, M., et al. 1994. Antimicrob. Agents Chemother. 38, 1470.
          Chen, M., et al. 1993. Antimicrob. Agents. Chemother. 37, 2550.
          Product Information
          CAS number58749-22-7
          ATP CompetitiveN
          FormYellow solid
          Hill FormulaC₂₁H₂₂O₄
          Chemical formulaC₂₁H₂₂O₄
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationLicochalcone-A, Synthetic, CAS 58749-22-7, is an estrogenic flavonoid with anti-tumor & antiparasitic properties. Reduces Bcl-2 expression and induces apoptosis in several human cancer cell lines.
          Biological Information
          Primary TargetAnti-tumor and antiparasitic properties
          Purity≥96% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Référence GTIN
          435800-10MG 04055977210309
          435800-50MG 04055977210316

          Documentation

          Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem Certificats d'analyse

          TitreNuméro de lot
          435800

          Références bibliographiques

          Aperçu de la référence bibliographique
          Rafi, M.M., et al. 2000. Anticancer Res. 20, 2653.
          Zhai, L., et al. 1999. J. Antimicrob. Chemother. 43, 793.
          Haraguchi, H., et al. 1998. Phytochemistry 48, 125.
          Park, E.J., et al. 1998. Planta Med. 64, 464.
          Chen, M., et al. 1994. Antimicrob. Agents Chemother. 38, 1470.
          Chen, M., et al. 1993. Antimicrob. Agents. Chemother. 37, 2550.

          Brochure

          Titre
          Caspases and other Apoptosis Related Tools Brochure
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-August-2008 RFH
          Synonyms(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
          DescriptionAn estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number58749-22-7
          Chemical formulaC₂₁H₂₂O₄
          Structure formulaStructure formula
          Purity≥96% by HPLC
          SolubilityDMSO (10 mg/ml) or Ethanol. Further dilute 1:10 with aqueous buffer or medium just prior to use.
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Harmful
          ReferencesRafi, M.M., et al. 2000. Anticancer Res. 20, 2653.
          Zhai, L., et al. 1999. J. Antimicrob. Chemother. 43, 793.
          Haraguchi, H., et al. 1998. Phytochemistry 48, 125.
          Park, E.J., et al. 1998. Planta Med. 64, 464.
          Chen, M., et al. 1994. Antimicrob. Agents Chemother. 38, 1470.
          Chen, M., et al. 1993. Antimicrob. Agents. Chemother. 37, 2550.