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420106 JAK3 Inhibitor III

JAK3 Inhibitor III : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97

420106
  
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      Aperçu

      Replacement Information
      Description
      Overview

      This product has been discontinued.

      Please refer to our complete listing of JAK3 inhibitors for possible alternatives. Please read all alternative product documentation carefully and contact technical service if you need additional information.





      A potent cell-permeable and specific inhibitor of JAK3 (IC50 = 11 µM). Inhibits JAK3 in immune complex kinase assays in a dose-dependent fashion and reduces the invasiveness of EGFR positive human cancer cells in a dose-dependent manner.
      Catalogue Number420106
      Brand Family Calbiochem®
      Synonyms4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97
      References
      ReferencesGhosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.
      Product Information
      CAS number211555-05-4
      FormPale yellow solid
      Hill FormulaC₁₆H₁₃Br₂N₃O₃
      Chemical formulaC₁₆H₁₃Br₂N₃O₃
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetJAK-3
      Primary Target IC<sub>50</sub>11 µM
      Purity≥92% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      420106 0

      Documentation

      JAK3 Inhibitor III Certificats d'analyse

      TitreNuméro de lot
      420106

      Références bibliographiques

      Aperçu de la référence bibliographique
      Ghosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-September-2007 JSW
      Synonyms4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97
      DescriptionA potent and specific inhibitor of JAK3 (IC50 = 11 µM). Inhibits JAK3 in immune complex kinase assays in a dose-dependent fashion.
      FormPale yellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number211555-05-4
      Chemical formulaC₁₆H₁₃Br₂N₃O₃
      Structure formulaStructure formula
      Purity≥92% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGhosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.