344280 Sigma-AldrichFostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem
An antitumor antibiotic that acts as a potent protein phosphatase 2A (PP2A) inhibitor (IC₅₀ = 3.2 nM).
More>> An antitumor antibiotic that acts as a potent protein phosphatase 2A (PP2A) inhibitor (IC₅₀ = 3.2 nM). Less<<Synonymes: FST, Phosphotrienin
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Aperçu
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Tableau de caractéristiques principal
CAS # | Empirical Formula |
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87860-39-7 | C₁₉H₂₆O₉PNa |
References | |
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References | Cheng, A., et al. 1998. Cancer Res. 58, 3611. Walsh, A.H., et al. 1997. FEBS Lett. 416, 230. Boritzki, T.J., et al. 1988. Biochem. Pharmacol. 37, 4063. |
Product Information | |
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CAS number | 87860-39-7 |
ATP Competitive | N |
Form | Colorless solid |
Hill Formula | C₁₉H₂₆O₉PNa |
Chemical formula | C₁₉H₂₆O₉PNa |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | PP2a |
Primary Target IC<sub>50</sub> | 3.2 nM, 131 µM, against protein phosphatase 2A (PP2A), protein phosphatase 1 (PP1), respectively |
Purity | ≥98% by HPLC |
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Cell permeable | N |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | UQ0600000 |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Référence | GTIN |
344280 | 0 |
Documentation
Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem FDS
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Fostriecin, Sodium Salt, Streptomyces pulveraceous - CAS 87860-39-7 - Calbiochem Certificats d'analyse
Titre | Numéro de lot |
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344280 |
Références bibliographiques
Aperçu de la référence bibliographique |
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Cheng, A., et al. 1998. Cancer Res. 58, 3611. Walsh, A.H., et al. 1997. FEBS Lett. 416, 230. Boritzki, T.J., et al. 1988. Biochem. Pharmacol. 37, 4063. |
Brochure
Titre |
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Protein Phosphatases Technical Bulletin |
Citations
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