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344514 FTase Inhibitor III

FTase Inhibitor III : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: H-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)

Primary Target: FTase
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Empirical Formula
      C₂₆H₃₆N₄O₅S₂
      Description
      Overview

      This product has been discontinued.





      A potent synthetic inhibitor of p21ras farnesyltransferase (FTase; IC50 = 12 nM).
      Catalogue Number344514
      Brand Family Calbiochem®
      SynonymsH-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)
      References
      ReferencesHamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
      Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.
      Product Information
      FormWhite solid
      Hill FormulaC₂₆H₃₆N₄O₅S₂
      Chemical formulaC₂₆H₃₆N₄O₅S₂
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetFTase
      Primary Target IC<sub>50</sub>12 nM
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceH-Cys-Val-2-Nal-Met-OH (Nal = naphthylalanine)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      344514 0

      Documentation

      FTase Inhibitor III Certificats d'analyse

      TitreNuméro de lot
      344514

      Références bibliographiques

      Aperçu de la référence bibliographique
      Hamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
      Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2008 RFH
      SynonymsH-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)
      DescriptionMost potent synthetic inhibitor of p21ras farnesyltransferase (FTase; IC50 = 12 nM).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₆H₃₆N₄O₅S₂
      Peptide SequenceH-Cys-Val-2-Nal-Met-OH (Nal = naphthylalanine)
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Solubility50% Acetic acid
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
      Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.

      Produits & Applications associés

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      Référence Description  
      344510 FTase Inhibitor I - Calbiochem Prix & Disponibilité

      Catégories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Farnesyltransferase (FTase), Geranylgeranyltransferase (GGTase), & Methyltransferase Inhibitors