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504820 Cinnabarinic acid - CAS 606-59-7 - Calbiochem

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CAS #Empirical Formula
606-59-7C₁₄H₈N₂O₆

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5.04820.0001
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      Description
      OverviewA partial, low-potency agonist highly selective for mGlu4 receptors (EC50 > 100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.
      Catalogue Number504820
      Brand Family Calbiochem®
      Synonyms2-Amino-3-oxo-3H-phenoxazine-1,9-di­carboxylic acid
      References
      ReferencesFazio, Francesco, et al. 2012. Mol. Pharmacol. 81, 643.
      Volpi, C., et al. 2012. Neuropharmacol. 63, 501.
      Hiramatsu, R., et al. 2008. J. Cell Biochem. 103, 42.
      Product Information
      CAS number606-59-7
      FormRed solid
      Hill FormulaC₁₄H₈N₂O₆
      Chemical formulaC₁₄H₈N₂O₆
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetmGlu₄ receptors
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      5.04820.0001 04055977243550

      Documentation

      Cinnabarinic acid - CAS 606-59-7 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Fazio, Francesco, et al. 2012. Mol. Pharmacol. 81, 643.
      Volpi, C., et al. 2012. Neuropharmacol. 63, 501.
      Hiramatsu, R., et al. 2008. J. Cell Biochem. 103, 42.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-July-2013 JSw
      Synonyms2-Amino-3-oxo-3H-phenoxazine-1,9-di­carboxylic acid
      DescriptionA partial, low-potency agonist highly selective for mGlu4 receptors (EC50 > 100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu4 receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.
      FormRed solid
      CAS number606-59-7
      Chemical formulaC₁₄H₈N₂O₆
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (25 mM). Slight warming is required for complete solubilization.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesFazio, Francesco, et al. 2012. Mol. Pharmacol. 81, 643.
      Volpi, C., et al. 2012. Neuropharmacol. 63, 501.
      Hiramatsu, R., et al. 2008. J. Cell Biochem. 103, 42.