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218800 Caspase-7, Human, Recombinant, E. coli

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218800
  
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      Aperçu

      Description
      OverviewRecombinant, human caspase-7 fused at the N- and C- termini to a His•Tag® sequence and expressed in E. coli as a single polypeptide. Subsequently undergoes spontaneous autoprocessing to yield the active enzyme. Useful for the study of enzyme regulation and kinetics, cleavage of target substrates, and inhibitor screening. MW: 12000 and 20000.
      M.W. 12,000 and 20,000 (heterodimer).
      Catalogue Number218800
      Brand Family Calbiochem®
      SynonymsMch3, ICE-LAP3
      References
      ReferencesStennicke, H.R., and Salvesen, G.S. 1997. J. Biol. Chem. 272, 25719.
      Product Information
      Unit of DefinitionOne unit is defined as the amount of enzyme that will cleave 1 nmol of Ac-DEVD-<i>p</i>NA (<a href ="/Products/ProductDisplay.asp→catNO=235400">Cat. No. 235400</a>) per hour at 37°C, pH 7.2.
      FormLyophilized
      Quality LevelMQ100
      Biological Information
      Specific Activity≥15,000 units/mg protein
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solitions are stable for up to 3 months at -70°C.
      Global Trade Item Number
      Référence GTIN
      218800 0