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14-719M CaM Kinase IIγ Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330, for use in Kinase Assays.

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14-719M
250 µg  Also available in 10 μg size (cat#14-719) and in bulk (cat#14-719-K).
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      Aperçu

      Replacement Information
      Description
      Catalogue Number14-719M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCaM Kinase IIγ Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, CaM Kinase IIγ, amino acids 1-330, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Entrez Gene Number
      Entrez Gene SummaryThe product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Six alternatively spliced variants that encode six different isoforms have been characterized to date. Additional alternative splice variants that encode different isoforms have been described, but their full-length nature has not been determined.
      Gene Symbol
      • CAMK2G
      • MGC26678
      • CAMKG
      • CAMK-II
      • CAMK
      • FLJ16043
      Protein TargetCaMKIIγ
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyCAMK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q13555 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.
      SIZE: 558 amino acids; 62609 Da
      SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
      SIMILARITY: SwissProt: Q13555 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
      Molecular Weight41.2kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-719) and in bulk (cat#14-719-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      14-719M 04053252441578

      Documentation

      Produits & Applications associés

      Alternative Packsize

      Référence Description  
      14-719 CaM Kinase IIγ Protein, active, 10 µg Prix & Disponibilité

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      Catégories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases