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ABC112 Anti-phospho-ULK1/ATG1 (Ser758) Antibody

Detect phospho-ULK1/ATG1 (Ser758) using this Anti-phospho-ULK1/ATG1 (Ser758) Antibody validated for use in Western Blotting, Peptide Inhibition Assay.

Anti-phospho-ULK1/ATG1 (Ser758) Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ULK1 UniProt Number: O75385
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ABC112
100 µL  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, PIARbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC112
      DescriptionAnti-phospho-ULK1/ATG1 (Ser758) Antibody
      Alternate Names
      • Serine/threonine-protein kinase ULK1
      • Autophagy-related protein 1 homolog
      • ATG1
      • hATG1
      • Unc-51-like kinase 1
      Background InformationULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1's enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.
      References
      Product Information
      FormatAffinity Purified
      Control
      • A431 and serum starved A431 cell lysates.
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect phospho-ULK1/ATG1 (Ser758) using this Anti-phospho-ULK1/ATG1 (Ser758) Antibody validated for use in Western Blotting, Peptide Inhibition Assay.
      Key Applications
      • Western Blotting
      • Peptide Inhibition Assay
      Application NotesPeptide Inhibition Analysis: A 1:1,000 dilution from a representative lot blocked phospho-ULK1/ATG1 (Ser758) in serum-starved A431 cell lysates.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human ULK1/ATG1 phosphorylated at Ser758.
      EpitopePhosphorylated Ser758
      HostRabbit
      SpecificityThis antibody recognizes the ULK1/ATG1 phosphorylated at Ser758.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Rat, and Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ULK1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~120 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in A431 and serum starved A431 cell lysates.

      Western Blot Analysis: A 1:1,000 dilution of this antibody detected ULK1/ATG1 on 10 µg of A431 and serum starved A431 cell lysates..
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABC112 04053252648816

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Anti-phospho-ULK1/ATG1 (Ser758) Antibody FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-phospho-ULK1/ATG1 (Ser758) Antibody Certificats d'analyse

      TitreNuméro de lot
      Anti-phospho-ULK1/ATG1 (Ser758) - 2420594 2420594
      Anti-phospho-ULK1/ATG1 (Ser758) - 3051524 3051524
      Anti-phospho-ULK1/ATG1 (Ser758) - 3754055 3754055
      Anti-phospho-ULK1/ATG1 (Ser758) -2504320 2504320
      Anti-phospho-ULK1/ATG1 (Ser758) -2571270 2571270
      Anti-phospho-ULK1/ATG1 (Ser758) Polyclonal Antibody 2942469

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies