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MABN1597 Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1

Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1 is an antibody against Olfactory Receptor 10G4 for use in Western Blotting.

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Research Category: Neuroscience Research Sub-Category: Sensory & PNS Gene Symbol: OR10G4 UniProt Number: Q8NGN3
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MABN1597
100 μg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN1597
      DescriptionAnti-Olfactory Receptor 10G4 Antibody, clone 6C11.1
      Alternate Names
      • Olfactory receptor OR11-278
      • Olfactory Receptor 10G4
      Background InformationOlfactory receptor 10G4 (UniProt Q8NGN3; also known as Olfactory receptor OR11-278) is encoded by the OR10G4 gene (Gene ID 390264) in human. Olfactory receptors belong to the class A rhodopsin-like family of G protein-coupled receptors (GPCRs). The human genome contains approximately 800 odorant receptor (OR) genes that have been shown to exhibit high genetic variability. Human has approximately 400 intact ORs, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. Odorant molecule binding induces an OR conformational change and interaction with the olfactory-type G protein, initiating downstream signaling that eventually results in an action potential from the depolarized OR neuron to the brain. Olfactory receptor 10G4 is a 311-amino acid protein with 4 extracellular domains (a.a. 1-23, 74-98, 160-196, 258-268), 7 transmembrane segments (a.a. 24-44, 53-73, 99-119, 139-159, 197-216, 237-257, 269-289), and 4 cytoplasmic regions (a.a. 45-52, 120-138, 217-236, 290-311).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Olfactory Receptor 10G4 Antibody, clone 6C11.1 is an antibody against Olfactory Receptor 10G4 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminal cytoplasmic tail of human Olfactory Receptor 10G4.
      EpitopeC-terminal cytoplasmic tail.
      Clone6C11.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • OR10G4
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~40 kDa observed. Target band size appears larger than the calculated molecular weight of 34.57 kDa due to glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human olfactory tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Olfactory Receptor 10G4 in 10 µg of human olfactory tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABN1597 04055977329469