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MABF1444 Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody

Anti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody is an antibody against KLRG1 for use in Flow Cytometry.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Klrg1, Mafa UniProt Number: O88713
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MABF1444
25 μg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFCSHmvioletFluor™ 450Monoclonal Antibody
      Description
      Catalogue NumberMABF1444
      DescriptionAnti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody
      Alternate Names
      • Killer cell lectin-like receptor subfamily G member 1
      • Mast cell function-associated antigen 2F1
      • KLRG1
      Background InformationThe 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).
      References
      Product Information
      FormatvioletFluor™ 450
      PresentationPurified Golden Syrian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationAnti-KLRG1 (mouse), violetFluor™ 450, clone 2F1 Antibody is an antibody against KLRG1 for use in Flow Cytometry.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      Clone2F1
      ConcentrationPlease refer to lot specific datasheet.
      HostSyrian Hamster
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Klrg1
      • Mafa
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.125 μg from a representative lot detected KLRG1 in one million C57Bl/6 splenocytes stained with PE Anti-mouse NK1.1.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABF1444 04055977291667

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies