Millipore Sigma Vibrant Logo

565610 SC-560 - CAS 188817-13-2 - Calbiochem

A cell-permeable, highly potent and selective inhibitor of COX-1 (IC₅₀ = 9 nM).

SC-560 - CAS 188817-13-2 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole

Primary Target: COX-1
View Products on Sigmaaldrich.com
565610
  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      188817-13-2C₁₇H₁₂CIF₃N₂O
      Description
      OverviewA cell-permeable, highly potent and selective inhibitor of COX-1 (IC50 = 9 nM). Inhibits COX-2 only at higher concentrations (IC50 = 6.3 µM).
      Catalogue Number565610
      Brand Family Calbiochem®
      Synonyms5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole
      References
      ReferencesOstrom, R.S., et al. 2001. Am. J. Physiol. Cell Physiol.281, C524.
      Smith, C.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13313.
      Product Information
      CAS number188817-13-2
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₁₇H₁₂CIF₃N₂O
      Chemical formulaC₁₇H₁₂CIF₃N₂O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCOX-1
      Primary Target IC<sub>50</sub>9 nM against COX-1
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze(-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      565610 0

      Documentation

      SC-560 - CAS 188817-13-2 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      SC-560 - CAS 188817-13-2 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      565610

      Referencias bibliográficas

      Visión general referencias
      Ostrom, R.S., et al. 2001. Am. J. Physiol. Cell Physiol.281, C524.
      Smith, C.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13313.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-April-2008 RFH
      Synonyms5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole
      DescriptionA cell-permeable, highly potent and selective inhibitor of cyclooxygenase-1 (COX-1; IC50 = 9 nM). Inhibits cyclooxygenase-2 (COX-2) only at higher concentrations (IC50 = 6.3 µM).
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number188817-13-2
      Chemical formulaC₁₇H₁₂CIF₃N₂O
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (200 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze(-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesOstrom, R.S., et al. 2001. Am. J. Physiol. Cell Physiol.281, C524.
      Smith, C.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13313.