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506272 SB 206553 Hydrochloride - CAS 158942-04-2 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553

Primary Target: 5-HT2C
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506272
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
158942-04-2C₁₇H₁₆N₄O·HCl

Precios y disponibilidad

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      Description
      OverviewA selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5 nM) and 5-HT2AR (Ki = 2,300 nM).
      Catalogue Number506272
      Brand Family Calbiochem®
      Synonyms5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553
      References
      ReferencesRos, R. et al. 2013. PNAS. 110, 348.
      Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
      Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.
      Product Information
      CAS number158942-04-2
      FormYellow solid
      Hill FormulaC₁₇H₁₆N₄O·HCl
      Chemical formulaC₁₇H₁₆N₄O·HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target5-HT2C
      Primary Target K<sub>i</sub>3.2 nM
      Secondary target5-HT2B
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      5.06272.0001 04055977243208

      Documentation

      SB 206553 Hydrochloride - CAS 158942-04-2 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Referencias bibliográficas

      Visión general referencias
      Ros, R. et al. 2013. PNAS. 110, 348.
      Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
      Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-September-2013 JSW
      Synonyms5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553
      DescriptionA selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5 nM) and 5-HT2AR (Ki = 2,300 nM).
      FormYellow solid
      CAS number158942-04-2
      Chemical formulaC₁₇H₁₆N₄O·HCl
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesRos, R. et al. 2013. PNAS. 110, 348.
      Knight, A. R. et al. 2004. Naunyn Schmiedebergs Arch. Pharmacol. 370, 114.
      Cussac, D. et al. 2002. Naunyn Schmiedebergs Arch. Pharmacol. 365, 242.