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GF311 RANTES Protein, Human Recombinant Animal Free

The RANTES protein, also known as CCL5 protein, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract & activate leukocytes. Manufactured using all non-animal reagents.

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UniProt Number: P13501 Entrez Gene Number: NM_002985.2
GF311
20 µg  
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      Descripción

      Replacement Information

      Tabla espec. clave

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF311
      DescriptionRANTES Protein, Human Recombinant Animal Free
      Alternate Names
      • CCL5
      • EoCP
      • Eosinophil chemotactic cytokine
      • SIS-delta
      • Small-inducible cytokine A5
      • T cell-specific protein P228
      Background InformationRANTES , also known as CCL5, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
      References
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ300
      Applications
      ApplicationThe RANTES protein, also known as CCL5 protein, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract & activate leukocytes. Manufactured using all non-animal reagents.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityNone
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      GF311 04053252691478

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      Categorías

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