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14-642M PTPMEG-1 Protein, 250 µg

N-terminal GST-tagged, recombinant, human PTPMEG-1, amino acids 423-end, for use in Phosphatase Assays.

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14-642M
250 µg  Also available in 10 μg size (cat#14-642) and in bulk (cat#14-642-K).
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-642M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPTPMEG-1 Protein, 250 µg
      OverviewN-Terminal GST-tagged, recombinant, human PTPMEG-1, amino acids 423-end
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationN-terminal GST-tagged, recombinant, human PTPMEG-1, amino acids 423-end, for use in Phosphatase Assays.
      Key Applications
      • Phosphatase Assay
      Biological Information
      Sourcerecombinant human PTPMEG-1, amino acids 423-end
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.
      Gene Symbol
      • PTPN4
      • MEG
      • PTPMEG1
      • PTPMEG
      • PTPase-MEG1
      Protein TargetPTPMEG-1
      Purification MethodGlutathione agarose affinity chromatography
      Target Sub-FamilyTyr phosphatase
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P29074 # May act at junctions between the membrane and the cytoskeleton.
      SIZE: 926 amino acids; 105911 Da
      SIMILARITY: SwissProt: P29074 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. & Contains 1 FERM domain. & Contains 1 PDZ (DHR) domain. & Contains 1 tyrosine-protein phosphatase domain.
      Molecular Weight83.1kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated in a PTPMEG-1 Phosphatase Assay
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-642) and in bulk (cat#14-642-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-642M 04053252924507

      Documentation

      Productos y aplicaciones relacionados

      Alternative Packsize

      Número de referencia Descripción  
      14-642 PTPMEG-1 Protein, 10 µg Precios y disponibilidad

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      Categorías

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
      Life Science Research > Proteins and Enzymes > Purified Phosphatases