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539522 PKCε Translocation Inhibitor Peptide - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₃₇H₆₅N₉O₁₃

Precios y disponibilidad

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539522-5MG
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      Description
      OverviewAn octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.
      Catalogue Number539522
      Brand Family Calbiochem®
      SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
      References
      ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
      Product Information
      ATP CompetitiveN
      DeclarationSold under license of U.S. Patent 5,783,405.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₃₇H₆₅N₉O₁₃
      Chemical formulaC₃₇H₆₅N₉O₁₃
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKCε Translocation
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      539522-5MG 04055977194630

      Documentation

      Licencias necesarias

      Título
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      PKCε Translocation Inhibitor Peptide - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      PKCε Translocation Inhibitor Peptide - Calbiochem Certificados de análisis

      CargoNúmero de lote
      539522

      Referencias bibliográficas

      Visión general referencias
      Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.

      Citas

      Título
    • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
    • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.
    • Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-September-2008 RFH
      SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
      DescriptionAn octapeptide that selectively inhibits the translocation of PKCε to subcellular sites. Inhibition of PKCε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₃₇H₆₅N₉O₁₃
      Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
      Purity≥97% by HPLC
      SolubilityH₂O (3 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
      Citation
    • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
    • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.