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14-508 PKCµ Recombinant Human Protein, Active, 10 µg

Active, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.

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14-508
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-508M when ordering the 250 µg size.
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-508
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPKCµ Recombinant Human Protein, Active, 10 µg
      OverviewN-terminal His6-tagged recombinant, full length, human PKCμ.
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceHuman PKCμ expressed in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryMembers of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]
      Gene Symbol
      • PRKD1
      • PKD
      • PKCM
      • nPKC-mu
      • PRKCM
      • PKC-mu
      • nPKC-D1
      • PKC-MU
      • PKD1
      Protein TargetPKCµ
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q15139 # This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
      SIZE: 912 amino acids; 101888 Da
      SUBUNIT: Interacts via its N-terminal region with CENTA1.
      PTM: Autophosphorylated (By similarity).
      SIMILARITY: SwissProt: Q15139 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 PH domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.
      Molecular Weight105kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of MAPKAP Kinase 2 Substrate Peptide
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-508M when ordering the 250 µg size.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-508 04053252366260

      Productos y aplicaciones relacionados

      Alternative Packsize

      Número de referencia Descripción  
      14-508M PKCµ Protein, active, 250 µg Precios y disponibilidad

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      Categorías

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases