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475913 Mycophenolic Acid - CAS 24280-93-1 - Calbiochem

Descripción

Tabla espec. clave

CAS #Empirical Formula
24280-93-1C₁₇H₂₀O₆

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
475913-100MG
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      Ampolla de plást. 100 mg
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      475913-500MG
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      Suspendido
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        El resto: se avisará
          El resto: se avisará
          Se avisará
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          Ampolla de plást. 500 mg
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          Description
          OverviewAn immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
          Catalogue Number475913
          Brand Family Calbiochem®
          Synonyms6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic Acid, MPA
          References
          ReferencesLangman, L.J., et al. 1995. Clin. Chem. 41, 295.
          Senda, M., et al. 1995. Transplantation 60, 1143.
          Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res. 204, 241.
          Falkner, F.G., and Moss, B. 1988. J. Virol. 62, 1849.
          Cohen, M.B., et al. 1981. J. Biol. Chem. 256, 8713.
          Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA 78, 2072.
          Product Information
          CAS number24280-93-1
          ATP CompetitiveN
          FormWhite to off-white solid
          Hill FormulaC₁₇H₂₀O₆
          Chemical formulaC₁₇H₂₀O₆
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Primary TargetInosine monophosphate dehydrogenase
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Safety Information according to GHS
          RTECSMP8050000
          Safety Information
          R PhraseR: 20/21/22-40

          Harmful by inhalation, in contact with skin and if swallowed.
          Limited evidence of a carcinogenic effect.
          S PhraseS: 22-36

          Do not breathe dust.
          Wear suitable protective clothing.
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Global Trade Item Number
          Número de referencia GTIN
          475913-100MG 04055977184822
          475913-500MG 04055977184150