Millipore Sigma Vibrant Logo

475820 Mitomycin C, Streptomyces caespitosus, Carrier-Free - CAS 50-07-7 - Calbiochem

Antibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Mitocin C, MMC

View Products on Sigmaaldrich.com
475820
  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      50-07-7C₁₅H₁₈N₄O₅
      Description
      OverviewAntibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastric cancer cells. Blocks the cell cycle at the G2 phase. Potency: ≥970 µg/mg.
      Catalogue Number475820
      Brand Family Calbiochem®
      SynonymsMitocin C, MMC
      References
      ReferencesKryt, F.A., et al. 1996. Blood 89, 938.
      Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
      Folnan, R.S., 1993. Oncology 50, 24.
      Tomasz, M., et al. 1987. Science 235, 1204.
      Product Information
      CAS number50-07-7
      FormPurple solid
      Hill FormulaC₁₅H₁₈N₄O₅
      Chemical formulaC₁₅H₁₈N₄O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityPotency: ≥ 970 μg/mg mitomycin C
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSCN0700000
      Safety Information
      R PhraseR: 28

      Very toxic if swallowed.
      S PhraseS: 36/37-45-28

      Wear suitable protective clothing and gloves.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      475820 0

      Documentation

      Mitomycin C, Streptomyces caespitosus, Carrier-Free - CAS 50-07-7 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Mitomycin C, Streptomyces caespitosus, Carrier-Free - CAS 50-07-7 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      475820

      Referencias bibliográficas

      Visión general referencias
      Kryt, F.A., et al. 1996. Blood 89, 938.
      Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
      Folnan, R.S., 1993. Oncology 50, 24.
      Tomasz, M., et al. 1987. Science 235, 1204.

      Folleto

      Cargo
      Caspases and other Apoptosis Related Tools Brochure
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-April-2010 JSW
      SynonymsMitocin C, MMC
      DescriptionAntibiotic and carcinostatic agent. Inhibits DNA synthesis by cross-linking DNA at guanine and adenine residues; disrupts base pairing. Induces apoptosis in gastic cancer cells. Blocks the cell cycle at the G2 phase.
      FormPurple solid
      CAS number50-07-7
      RTECSCN0700000
      Chemical formulaC₁₅H₁₈N₄O₅
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Biological activityPotency: ≥ 970 μg/mg mitomycin C
      SolubilityH₂O (<1 mg/ml) or Methanol (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Highly Toxic & Carcinogenic / Teratogenic
      Merck USA index14, 6215
      ReferencesKryt, F.A., et al. 1996. Blood 89, 938.
      Schwartz, G.K., et al. 1995. J. Natl. Cancer Inst. 87, 1394.
      Folnan, R.S., 1993. Oncology 50, 24.
      Tomasz, M., et al. 1987. Science 235, 1204.