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FCMAB184F Milli-Mark™ Anti-CD19 -FITC Antibody, clone HD37

Detect CD19 using this Milli-Mark Anti-CD19 -FITC Antibody, clone HD37 validated for use in FC.

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Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P15391
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FCMAB184F
100 tests  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMFITCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB184F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD19 -FITC Antibody, clone HD37
      Alternate Names
      • Differentiation antigen CD19
        B-lymphocyte surface antigen B4
        T-cell surface antigen Leu-12
      • B-lymphocyte antigen CD19
      Background InformationCD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
      Product Information
      FormatFITC
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Quality LevelMQ100
      Applications
      ApplicationDetect CD19 using this Milli-Mark Anti-CD19 -FITC Antibody, clone HD37 validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenHairy cell leukemia cells
      CloneHD37
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD19.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight120kDa (Pezzutto, 1987; Sato, 1997)
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Global Trade Item Number
      Número de referencia GTIN
      FCMAB184F 04053252746369