573129 Sigma-AldrichInSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem
The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The InSolution™ STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Productos recomendados
Descripción
| Replacement Information |
|---|
Tabla espec. clave
| Empirical Formula |
|---|
| C₁₇H₁₄BrN₃O |
Precios y disponibilidad
| Número de referencia | Disponiblidad | Embalaje | Cant./Env. | Precio | Cantidad | |
|---|---|---|---|---|---|---|
| 573129-5MG |
|
Frasco de vidrio | 5 mg |
|
— |
| Description | |
|---|---|
| Overview | A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo. |
| Catalogue Number | 573129 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
| Product Information | |
|---|---|
| Form | Liquid |
| Formulation | A 50 mM (5 mg/281 µl) solution of STAT3 Inhibitor III, WP1066 (Cat. No. 573097) in DMSO. |
| Hill Formula | C₁₇H₁₄BrN₃O |
| Chemical formula | C₁₇H₁₄BrN₃O |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥97% by HPLC |
| Physicochemical Information |
|---|
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information | |
|---|---|
| R Phrase | R: 36/38 Irritating to eyes and skin. |
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Número de referencia | GTIN |
| 573129-5MG | 04055977190199 |
Documentation
InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem Ficha datos de seguridad (MSDS)
| Título |
|---|
InSolution™ STAT3 Inhibitor III, WP1066 - Calbiochem Certificados de análisis
| Cargo | Número de lote |
|---|---|
| 573129 |
Referencias bibliográficas
| Visión general referencias |
|---|
| Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
Licencias necesarias e Información técnica
| Cargo |
|---|
| JAK/STAT Signaling Research Focus |
| Ficha técnica | ||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|