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505275 ICI 118551 Hydrochloride - CAS 72795-01-8 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos:  (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride

Primary Target: →2 adrenergic receptors
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505275
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Tabla espec. clave

CAS #Empirical Formula
72795-01-8C₁₇H₂₇NO₂ • HCl

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      Description
      OverviewA highly selective antagonist for the β2 adrenergic receptors. Binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively).
      Catalogue Number505275
      Brand Family Calbiochem®
      Synonyms (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride
      References
      ReferencesBilski, A., et al. 1983. J. Cardiovasc. Pharmacol. 5, 430.
      Cook, S. et al. 1993. Br. J .Pharmacol. 109, 1140.
      Ten Berge, R., et al. 1995. Eur. J. Pharmacol. 275, 199.
      Strosberg, A., et al. 1996. TiPS 17, 373.
      Product Information
      CAS number72795-01-8
      FormWhite solid
      Hill FormulaC₁₇H₂₇NO₂ • HCl
      Chemical formulaC₁₇H₂₇NO₂ • HCl
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target→2 adrenergic receptors
      Primary Target K<sub>i</sub>1.2, 120 and 257 nM for →2, →1 and →3 receptors respectively.
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      5.05275.0001 04055977263527

      Documentation

      ICI 118551 Hydrochloride - CAS 72795-01-8 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Referencias bibliográficas

      Visión general referencias
      Bilski, A., et al. 1983. J. Cardiovasc. Pharmacol. 5, 430.
      Cook, S. et al. 1993. Br. J .Pharmacol. 109, 1140.
      Ten Berge, R., et al. 1995. Eur. J. Pharmacol. 275, 199.
      Strosberg, A., et al. 1996. TiPS 17, 373.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-July-2019 JSW
      Synonyms (±)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride
      DescriptionA highly selective antagonist for the β2 adrenergic receptors. Binds to the β2 subtype with at least 100 times greater affinity than β1 or β3, the two other known subtypes of the beta adrenoceptor. (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number72795-01-8
      Chemical formulaC₁₇H₂₇NO₂ • HCl
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBilski, A., et al. 1983. J. Cardiovasc. Pharmacol. 5, 430.
      Cook, S. et al. 1993. Br. J .Pharmacol. 109, 1140.
      Ten Berge, R., et al. 1995. Eur. J. Pharmacol. 275, 199.
      Strosberg, A., et al. 1996. TiPS 17, 373.