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EZBRAIN-SET Human Amyloid β40 and Amyloid β42 Brain ELISA

This Human Amyloid β40 & Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β40 & Amyloid β42 levels in Neuroscience research.

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Key Applications: ELISA Detection Methods: Colorimetric Research Category: Neuroscience Research Sub-Category: Alzheimer's Disease
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EZBRAIN-SET
96-well plate  
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      Descripción

      Replacement Information

      Tabla espec. clave

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Amyloid β40 Amyloid β42 HELISAColorimetric
      Description
      Catalogue NumberEZBRAIN-SET
      DescriptionHuman Amyloid β40 and Amyloid β42 Brain ELISA
      Background InformationAmyloid beta peptides have been implicated in the etiology of Alzheimer’s disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore’s Human Amyloid β40 and Amyloid β42 Brain ELISA kits are used for the measurement of Amyloid beta 40 and Amyloid beta 42 in brain samples and for other tissue samples in a 96-well format. These assays are for research use only and appropriate for the in vitro detection of human Amyloid β40 and Amyloid β42 peptides in brain samples from e.g. Guinea pig, transgenic hAmyloid mice and cell extracts
      References
      Product Information
      Detection methodColorimetric
      Precision, %
      • Intra-assay <10
      • Inter-assay <10
      Quality LevelMQ200
      Applications
      ApplicationThis Human Amyloid β40 & Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β40 & Amyloid β42 levels in Neuroscience research.
      Key Applications
      • ELISA
      Application NotesThese assays require 50 µl of sample and are overnight assays.
      Biological Information
      SpecificityThe Amyloid β40 ELISA uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-40, which causes a high selectivity for Aβ 40. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-42, Aβ1-43 and Aβ1-44.

      The Amyloid β42 ELISA uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-42, Aβ1-43 and Aβ1-44.
      Species Reactivity
      • Human
      Analytes Available
      • Amyloid β40
      • Amyloid β42
      Gene Symbol
      • APP
      Physicochemical Information
      Sensitivity
      • The lowest level of Amyloid β1-40 standard used in this assay is 6.0 pg/mL (50 μL sample size).
      • The lowest level of Amyloid ß1-42 standard used in this assay is 8 pg/mL (50 μL sample size).
      Linearity of DilutionContact technical support for information
      Standard Curve Range
      • 16 pg/mL – 500 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Storage ConditionsComponents in the kit can be stored up to 2 weeks at 2-8°C
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      EZBRAIN-SET 04053252005558

      Productos y aplicaciones relacionados

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      Número de referencia Descripción  
      EZBRAIN40 Human Amyloid β40 Brain ELISA Precios y disponibilidad
      EZBRAIN42 Human Amyloid β42 Brain ELISA Precios y disponibilidad

      Categorías

      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits