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368059 Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem

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Precios y disponibilidad

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368059-1MG
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      368059-5MG
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          Description
          OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
          Catalogue Number368059
          Brand Family Calbiochem®
          SynonymsZ-IETD-AFC, Caspase-8 Substrate II
          References
          ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
          Product Information
          CAS number219138-02-0
          ATP CompetitiveN
          FormWhite lyophilized solid
          Hill FormulaC₃₇H₄₂F₃N₅O₁₃
          Chemical formulaC₃₇H₄₂F₃N₅O₁₃
          ReversibleN
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          368059-1MG 07790788049621
          368059-5MG 04055977192179

          Documentation

          Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          368059

          Referencias bibliográficas

          Visión general referencias
          Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

          Folleto

          Cargo
          Caspases and other Apoptosis Related Tools Brochure
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-July-2008 RFH
          SynonymsZ-IETD-AFC, Caspase-8 Substrate II
          DescriptionA fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
          FormWhite lyophilized solid
          CAS number219138-02-0
          Chemical formulaC₃₇H₄₂F₃N₅O₁₃
          Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
          Purity≥97% by HPLC
          SolubilityDMSO (1 mg/ml)
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

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          Categorías

          Life Science Research > Inhibitors and Biochemicals