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344273 Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride - CAS 115116-37-5 - Calbiochem

Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride, CAS 115116-37-5, is a chemically-modified forskolin for greater stability and water solubility.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: L-858051, 8,13-Epoxy-7β-(N-methylpiperazino-γ-butyryloxy)-1α,6β,9α-trihydroxy-labd-14-en-11-one, 2HCl

Primary Target: Adenylate cyclase
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Replacement Information

Tabla espec. clave

CAS #Empirical Formula
115116-37-5C₂₉H₄₈N₂O₇ · 2HCl

Precios y disponibilidad

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      344273-5MG
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          Description
          OverviewChemically-modified forskolin with greater stability and water solubility than the parent compound. Activates adenylate cyclase (EC50 = 13 µM). Inhibits 5HT-stimulated inositol phosphate accumulation in smooth muscle cells.
          Catalogue Number344273
          Brand Family Calbiochem®
          SynonymsL-858051, 8,13-Epoxy-7β-(N-methylpiperazino-γ-butyryloxy)-1α,6β,9α-trihydroxy-labd-14-en-11-one, 2HCl
          References
          ReferencesYang, C.M., et al. 1999. Cell Signal. 11, 697.
          Hartzell, H.C., and Budnitz, D. 1992. Mol. Pharmacol. 41, 880.
          Chidiac, P., et al. 1991. J. Mol. Cell. Cardiol. 23, 1255.
          Laurenza, A., et al. 1987. Mol. Pharmacol. 32, 133.
          Product Information
          CAS number115116-37-5
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₉H₄₈N₂O₇ · 2HCl
          Chemical formulaC₂₉H₄₈N₂O₇ · 2HCl
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ200
          Applications
          ApplicationForskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride, CAS 115116-37-5, is a chemically-modified forskolin for greater stability and water solubility.
          Biological Information
          Primary TargetAdenylate cyclase
          Primary Target IC<sub>50</sub>EC50 = 13 µM in activating adenylate cyclase
          Purity≥92% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 21

          Harmful in contact with skin.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +15°C to +30°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          344273-10MG 04055977215380
          344273-5MG 04055977214642

          Documentation

          Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride - CAS 115116-37-5 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-, Dihydrochloride - CAS 115116-37-5 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          344273

          Referencias bibliográficas

          Visión general referencias
          Yang, C.M., et al. 1999. Cell Signal. 11, 697.
          Hartzell, H.C., and Budnitz, D. 1992. Mol. Pharmacol. 41, 880.
          Chidiac, P., et al. 1991. J. Mol. Cell. Cardiol. 23, 1255.
          Laurenza, A., et al. 1987. Mol. Pharmacol. 32, 133.

          Folleto

          Cargo
          Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision31-March-2011 RFH
          SynonymsL-858051, 8,13-Epoxy-7β-(N-methylpiperazino-γ-butyryloxy)-1α,6β,9α-trihydroxy-labd-14-en-11-one, 2HCl
          DescriptionA chemically modified forskolin with greater stability and water solubility. Activates adenylate cyclase (EC50 = 13 µM).
          FormWhite solid
          CAS number115116-37-5
          Chemical formulaC₂₉H₄₈N₂O₇ · 2HCl
          Structure formulaStructure formula
          Purity≥92% by HPLC
          SolubilityMethanol or H₂O (12 mg/ml)
          Storage +15°C to +30°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.
          Toxicity Harmful
          ReferencesYang, C.M., et al. 1999. Cell Signal. 11, 697.
          Hartzell, H.C., and Budnitz, D. 1992. Mol. Pharmacol. 41, 880.
          Chidiac, P., et al. 1991. J. Mol. Cell. Cardiol. 23, 1255.
          Laurenza, A., et al. 1987. Mol. Pharmacol. 32, 133.