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341600 Fibrinogen, Fragment D, Human Plasma

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341600
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341600-200UG
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      Ampolla de plást. 200 μg
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      Description
      OverviewNative fibrinogen fragment D from human plasma prepared by plasmin digestion of purified fibrinogen followed by preparative electrophoresis. Thermolabile core fragment of fibrinogen. Complete proteolysis of a single fibrinogen molecule produces two D and one E fragments. The D and E fragments have no common antigenic determinants; therefore, no cross-reaction occurs. Reported to increase endothelial membrane permeability to albumin.
      Catalogue Number341600
      Brand Family Calbiochem®
      References
      ReferencesSpraggon, G., et al. 1997. Nature 389, 455.
      Stirk, C.M., et al. 1993. Atherosclerosis 103, 159.
      Vogel, P., et al. 1993. Eur. Surg. Res. 25, 83.
      Azpiazu, I., and Chapman, D. 1992. Biochim. Biophys. Acta 1119, 268.
      Thompson, W.D., et al. 1992. J. Pathol. 168, 47.
      Fisher, E.G., et al. 1991. Haemostasis 21, 141.
      Ge, M., et al. 1991. Am. J. Physiol. 261, L283.
      Product Information
      FormLyophilized
      FormulationLyophilized from 400 mM glycine, 150 mM NaCl.
      Quality LevelMQ200
      Applications
      ApplicationFibrinogen fragment D is a thermolabile native human plasma protein prepared by digestion of purified fibrinogen followed by preparative electrophoresis.
      Biological Information
      Puritysingle band by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      ContaminantsFragment E: ≤1%
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 4 h at 20°C or for up to 8 h at 4°C or for up to 3 months at -70°C.
      Global Trade Item Number
      Número de referencia GTIN
      341600-200UG 04055977195187