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14-473M Fes/Fps Protein, active, 250 µg

Active, recombinant full length human Fes, containing an N-terminal His6-tag, for use in Kinase Assays.

Fes/Fps Protein, active, 250 µg: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
14-473M
250 µg  Also available in 10 μg size (cat#14-473) and in bulk (cat# 14-473-K).
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-473M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionFes/Fps Protein, active, 250 µg
      OverviewRecombinant full length human Fes, containing an N-terminal His6-tag
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, recombinant full length human Fes, containing an N-terminal His6-tag, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
      Gene Symbol
      • FES
      • FPS
      • C-Fes
      Protein TargetFes/Fps
      Purification MethodNi-NTA agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummarySIZE: 822 amino acids; 93497 Da
      SIMILARITY: SwissProt: P07332 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. & Contains 1 FCH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain.
      Molecular Weight98kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of the Poly (Glu4-Tyr) (4:1) substrate
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -70C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-473) and in bulk (cat# 14-473-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-473M 04053252330124

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      Número de referencia Descripción  
      14-473 Fes/Fps Protein, active, 10 µg Precios y disponibilidad

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      Categorías

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases