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233526 Coagulation Factor Xa, Human Plasma

Coagulation Factor Xa, Human Plasma, CAS 9002-05-5, is a native coagulation factor Xa prepared from Factor X by activation with Russel's viper venom. The venom is removed after activation.

Coagulation Factor Xa, Human Plasma: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
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233526
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233526-10U
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      Description
      OverviewNative coagulation factor Xa from human plasma prepared from homogeneous Factor X by activation with Russel’s viper venom. The venom is removed after activation. During coagulation, in the presence of Ca2+ and membrane phospholipids, a complex of Factor Xa and Factor Va (the prothrombinase complex) activates prothrombin to thrombin. Inhibitors include AEBSF (Cat. No. 101500), DFP (Cat. No. 30967), PMSF (Cat. No. 52332), and Soybean Trypsin Inhibitor (Cat. No. 650357). Sold on the basis of plasma equivalent units of Factor X. 100 plasma equivalent units are equal to 800 µg of Factor X.
      Catalogue Number233526
      Brand Family Calbiochem®
      References
      ReferencesHeeb, M.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 2728.
      Lindhout, T., et al. 1994. Biochem. J. 297, 131.
      Morishita, H., et al. 1994. Thrombosis Res. 73, 193.
      Lupu, C., et al. 1993. Thrombosis Haemostasis 70, 579.
      Jordan, S.P., et al. 1992. Biochemistry 31, 5374.
      Schoen, P., et al. 1992. Br. J. Haemotol. 81, 255.
      Tracy, P.B., et al. 1992. Methods Enzymol. 215, 329.
      Lawson, J.H., and Mann, K.G. 1991. J. Biol. Chem. 226, 11317.
      Tans, G., et al. 1991. J. Biol. Chem. 266, 21864.
      Owen, W.G., et al. 1974. J. Biol. Chem. 249, 594.
      Product Information
      CAS number9002-05-5
      Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol CHROMOZYM<sup>®</sup> X substrate per min at 25°C.
      EC number3.4.21.6
      FormLyophilized
      FormulationLyophilized from 700 mM NaCl, 20 mM Tris-HCl, pH 7.4.
      Quality LevelMQ100
      Biological Information
      Purityhomogeneous by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥170 units/mg protein
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
      Global Trade Item Number
      Número de referencia GTIN
      233526-10U 04055977217889