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219372 Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
429676-93-7C₃₆H₃₃N₂O₆P

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
219372-1MG
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      Ampolla de plást. 1 mg
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      219372-5MG
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      Debe confirmarse disponibilidad
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          Frasco de vidrio 5 mg
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          Description
          OverviewA potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
          Catalogue Number219372
          Brand Family Calbiochem®
          References
          ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
          Product Information
          CAS number429676-93-7
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₃₆H₃₃N₂O₆P
          Chemical formulaC₃₆H₃₃N₂O₆P
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationCathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).
          Biological Information
          Primary Targetcathepsin G
          Primary Target IC<sub>50</sub>53 nM
          Primary Target K<sub>i</sub>63 nM for cathepsin G
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          219372-1MG 04055977202267
          219372-5MG 04055977202274

          Documentation

          Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          219372

          Referencias bibliográficas

          Visión general referencias
          Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-April-2011 RFH
          DescriptionA potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM). Weakly inhibits chymotrypsin (Ki = 1.5 µM) and does not have any significant inhibitory effect on thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number429676-93-7
          Chemical formulaC₃₆H₃₃N₂O₆P
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (5 mg/ml) or Methanol
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.