Millipore Sigma Vibrant Logo

219385 Cathepsin B Inhibitor II - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₁₉H₃₆N₄O₄

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
219385-1MG
Comprobando disponibilidad...
Disponibilidad a confirmar
Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Ampolla de plást. 1 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      Solicitar precio
      Description
      OverviewA more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) compared to leupeptin (IC50 = 310 nM).
      Note: this peptide forms cyclic isomers.
      Catalogue Number219385
      Brand Family Calbiochem®
      SynonymsAc-LVK-CHO
      References
      ReferencesMcConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₉H₃₆N₄O₄
      Chemical formulaC₁₉H₃₆N₄O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcathepsin B
      Primary Target IC<sub>50</sub>4 nM against cathepsin B
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Leu-Val-lysinal
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      219385-1MG 04055977201666

      Documentation

      Cathepsin B Inhibitor II - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Cathepsin B Inhibitor II - Calbiochem Certificados de análisis

      CargoNúmero de lote
      219385

      Referencias bibliográficas

      Visión general referencias
      McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

      Folleto

      Cargo
      Cathepsins and Related Products Technical Bulletin

      Citas

      Título
    • Moin U Fareed, et al. (2006) Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 290, R1589-R1597.
    • Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-October-2007 RFH
      SynonymsAc-LVK-CHO
      DescriptionLysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) than of leupeptin (IC50 = 310 nM). Note: this peptide forms cyclic isomers.
      FormWhite solid
      Chemical formulaC₁₉H₃₆N₄O₄
      Peptide SequenceAc-Leu-Val-lysinal
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.
      Toxicity Standard Handling
      ReferencesMcConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.
      Citation
    • Moin U Fareed, et al. (2006) Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. American Journal of Physiology Regulatory, Integrative and Comparative Physiology 290, R1589-R1597.