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14-689M Casein Kinase 2α2 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2, for use in Kinase Assays.

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14-689M
250 µg  Also available in 10 μg size (cat#14-689) and in bulk (cat#14-689-K).
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-689M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCasein Kinase 2α2 Protein, active, 250 µg
      OverviewN-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 cells
      Entrez Gene Number
      Gene Symbol
      • CSNK2A2
      • CK2A2
      • CSNK2A1
      • FLJ43934
      Protein TargetCK2α2
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyCMGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P19784 # Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
      SIZE: 350 amino acids; 41213 Da
      SUBUNIT: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
      SIMILARITY: SwissProt: P19784 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. & Contains 1 protein kinase domain.
      Molecular Weight45.8kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of casein kinase 2 substrate peptide
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditionsstable for 6 months at -70°C from date of shipment
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-689) and in bulk (cat#14-689-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-689M 04053252925337

      Documentation

      Productos y aplicaciones relacionados

      Alternative Packsize

      Número de referencia Descripción  
      14-689 Casein Kinase 2α2 Protein, active, 10 µg Precios y disponibilidad

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      Categorías

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases