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SCT050 BioTracker DCM-Bgal Live Cell Dye

Near-Infrared live cell imaging dye for visualization of beta-Galactosidase activity, an important marker for cell senescence and primary ovarian cancers.

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SCT050
1 mg  
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      Descripción

      Replacement Information
      Description
      Catalogue NumberSCT050
      DescriptionBioTracker DCM-Bgal Live Cell Dye
      OverviewThe BioTracker DCM-Bgal live cell dye is a ratiometric near-infrared (NIR) dye for the real-time fluorescent quantification of beta-galatosidase (ß-gal) enzyme activity in vitro, in vivo and in situ.

      ß-galactosidase is an important marker for cell senescence and primary ovarian cancers. BioTracker DCM-Bgal live cell dye has light-up ratiometric NIR fluorescence with
      large Stokes shift, high photostability than commercial ICG, and pH independency under the physiological range, allowing for the real-time
      evaluation of β-gal activity. DCM-βgal displays higher affinity for β-gal
      than commercial X-gal and much faster response to β-gal than
      the previously reported FDG.

      Spectral Properties
      NIR fluorescence images obtained from 605 to 725 nm, λex = 560 nm

      References
      Gu K et al. Real-Time Tracking and In Vivo Visualization of ß-galactosidase Activity in Colorectal Tumor with a ratiometric Near-Infrared Fluorescent Probe. J. Am. Chem. Soc. 2016, 138, 5334-5340.
      Alternate Names
      • Live cell imaging probe
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized
      Applications
      ApplicationNear-Infrared live cell imaging dye for visualization of beta-Galactosidase activity, an important marker for cell senescence and primary ovarian cancers.
      Key Applications
      • Cell Based Assays
      • Fluorescence
      Application NotesLive cell fluorescent imaging
      Biological Information
      ConcentrationPlease refer to lot specific datasheet.
      Molecular Weight474.5 g/mol
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity: ≥ 98% confirmed by HPLC. LC-MS and HNMR confirms structure. Molar Mass: 474.5 g/mol
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker DCM-Bgal Live Cell Dye at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      SCT050 04061841072768