Millipore Sigma Vibrant Logo

200484 Bestatin - CAS 58970-76-6 - Calbiochem

Bestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.

Bestatin - CAS 58970-76-6 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu

Primary Target: amino peptidase b
View Products on Sigmaaldrich.com
200484
Ver precios y disponibilidad

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
58970-76-6C₁₆H₂₄N₂O₄

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
200484-10MG
Comprobando disponibilidad...
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      		 Ampolla de plást. 10 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      —
      Solicitar precio
      		 —
      Description
      OverviewBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Also available as a 50 mM solution in water (Cat. No. 200488).
      Catalogue Number200484
      Brand Family Calbiochem®
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      References
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Product Information
      CAS number58970-76-6
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₁₆H₂₄N₂O₄
      Chemical formulaC₁₆H₂₄N₂O₄
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationBestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.
      Biological Information
      Primary Targetamino peptidase b
      Purity>99% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSOH2915000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      200484-10MG 04055977221459

      Documentation

      Bestatin - CAS 58970-76-6 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Bestatin - CAS 58970-76-6 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      200484

      Referencias bibliográficas

      Visión general referencias
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.

      Citas

      Título
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2013 JSW
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      DescriptionBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM.
      FormWhite crystalline solid
      CAS number58970-76-6
      RTECSOH2915000
      Chemical formulaC₁₆H₂₄N₂O₄
      Purity>99% by HPLC
      SolubilityDMSO (2 mg/ml) or Methanol (5 mg/ml). Unstable in aqueous solution; dilute just prior to use.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 9842
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Citation
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•