Millipore Sigma Vibrant Logo

EI3 Antipain

Antipain: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
View Products on Sigmaaldrich.com
EI3
100 mg  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information
      Description
      Catalogue NumberEI3
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAntipain
      OverviewAntipain is a serine and cysteine reversible protease inhibitor. It inhibits papain and trypsin. Plasmin is inhibited to a small extent as well. More specific than leupeptin for papain and trypsin.

      Sequence:

      [(S)-1-Carboxy-2-Phenylethyl]-Carbamoyl-L-Arg-L-Val-Argininal-HCL-2H2O.

      M.W: 604.71

      Working solutions: 1-100μM.

      Specific Activity: Varies with lot, IC50 is approximately 0.20μg/mL (papain/casein, pH 7.4 37°C).

      Stable for several hours. Stock solutions of 10mM in water or buffer are stable for 1 week at 4ºC, 1 month at -20ºC. Also soluable in MeOH or DMSO.

      5mg/827 microliters of water = 10mM solution. Dilute 1:100 for a 100μM solution.

      Source: Microbial origin. Not synthetically made.
      References
      Product Information
      PresentationLyophilized no preservatives.

      Properties: Soluble in H2O, methanol and DMSO (Stock solution: 10 mM). Stable at -20° C.

      Mechanism of action: Formation of a hemicetal adduct between the aldehyde group of the inhibitor and the active serine of the proteinase.

      Inhibition spectrum: Inhibits papain, trypsin and plasmin to a lesser extent. More specific for papain and trypsin than leupeptin. The inhibitory potency of antipain is 100-fold higher than that of elastatinal.

      Pale yellow powder; material is isolated from cultured media of microorganisms. As with many of these compounds, they are too inherently unstable to allow for high standards of purity. The homogeneity of these compounds cannot be guaranteed except for their specific inhibitory activities.
      Quality LevelMQ100
      Applications
      Key Applications
      • Inhibits Activity/Function
      Application NotesProteinase inhibitor; Inhibits papain and trypsin. Plasmin is inhibited to a small extent.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancepH 1% aqueous solution: 5.2
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain dry at -20ºC for up to 18 months. Store reconstituted product in aliquots at -20ºC for up to 9 months. Do not thaw and refreeze.
      Packaging Information
      Material Size100 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      EI3 04053252508844

      Documentation

      Antipain Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Antipain Certificados de análisis

      CargoNúmero de lote
      ANTIPAIN PROTEASE INHIBITOR 3084128
      ANTIPAIN PROTEASE INHIBITOR 2971062
      ANTIPAIN PROTEASE INHIBITOR 2905625
      ANTIPAIN PROTEASE INHIBITOR 2470385
      ANTIPAIN PROTEASE INHIBITOR - 2088955 2088955
      ANTIPAIN PROTEASE INHIBITOR - 2278482 2278482
      ANTIPAIN PROTEASE INHIBITOR - 3207642 3207642
      ANTIPAIN PROTEASE INHIBITOR - 3284295 3284295
      ANTIPAIN PROTEASE INHIBITOR - 3385781 3385781
      ANTIPAIN PROTEASE INHIBITOR - 3482807 3482807
      Show more

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Antipain, a new protease inhibitor isolated from actinomycetes. {original article}
      Suda, H., et al.
      J. Antibiotics (Tokyo), 25:263-266 (1972)  1971

      		4559651 4559651
      Structure of antipain, a new Sakaguchi-positive product of streptomyces {Structure}
      Umezawa, S et al.
      J. Antibiotics (Tokyo), 25(4):267-270 (1972)  1971

      		5052959 5052959

      Ficha técnica

      Cargo
      ANTIPAIN PROTEASE INHIBITOR