Millipore Sigma Vibrant Logo

06-1358 Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody

Use Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody (Rabbit Polyclonal Antibody) validated in WB & DB to detect acetyl (Lys34) phospho (Ser36) Histone H1 also known as Histone H1b.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Histones Gene Symbol: HIST1H1E, H1F4 UniProt Number: P10412
View Products on Sigmaaldrich.com
06-1358
200 µL  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Ofertas especiales

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Ofertas especiales

      100% Performance Guaranteed

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, HWB, DBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number06-1358
      DescriptionAnti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody
      Alternate Names
      • Histone H1.4
      • Histone H1b
      Background InformationH1.4 is one of four variants of histone H1 (H1.2-H1.5) that is found in somatic cells. The H1 histones may function as linker proteins binding DNA via their GH domain, and enabling the wrapping of DNA around the core nucleosomal structure formed from the association of H2A, H2B, H3, and H4. In response to various stimuli, histones undergo a number of post-translational modifications (PTM) including acetylation, phoshorylation, and methylation. Previous studies have suggested that H1.4 may be phosphorylated during mitosis and interphase resulting in increased transcription of target genes by RNA polymerase I and II, and therefore this PTM on H1.4 may have implications for cell growth. H1.4 may also undergo acetylation of its N-terminal lysine residues. Often, it is the pattern of different modifications on several histone residues that alter chromatin and affect gene expression, rather than modification of single residues.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Calf thymus histone extract
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationUse Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody (Rabbit Polyclonal Antibody) validated in WB & DB to detect acetyl (Lys34) phospho (Ser36) Histone H1 also known as Histone H1b.
      Key Applications
      • Western Blotting
      • Dot Blot
      Application NotesDot Blot Specificity Analysis: Unmodified and various modified Histone peptides (see Table) were probed with acetyl (Lys34) phospho (Ser36) Histone H1.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Histone H1 acetylated at Lys34 and phosphorylated at Ser36.
      EpitopeAcetylated Lys34 and phosphorylated Ser36
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes Histone H1 acetylated at Lys34 and phosphorylated at Ser36.
      Species Reactivity
      • Bovine
      • Human
      Species Reactivity NoteDemonstrated to react with Bovine and Human. Predicted to react with Canine and Rhesus macaque based on 100% sequence homology. Other homologies: Mouse and Rat (90% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HIST1H1E
      • H1F4
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~34 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in calf thymus histone extract.

      Western Blot Analysis: A 1:37 dilution of this antibody detected Histone H1 on 10 µg of calf thymus histone extract.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      06-1358 04053252648458

      Documentation

      Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-acetyl (Lys34) phospho (Ser36) Histone H1 Antibody Certificados de análisis

      CargoNúmero de lote
      Anti-acetyl (Lys34) phospho (Ser36) Histone H1 - 3949235 3949235
      Anti-acetyl (Lys34) phospho (Ser36) Histone H1 - Q2025111 Q2025111

      Licencias necesarias e Información técnica

      Cargo
      White Paper - The Message in the Marks: Deciphering Cancer Epigenetics

      Productos y aplicaciones relacionados

      Related Products

      Número de referencia Descripción  
      06-1372 Anti-acetyl (Lys26) phospho (Ser27) Histone H1.4 Antibody Precios y disponibilidad
      MAB1276 Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1 Precios y disponibilidad
      MAB3864 Anti-DNA/Histone H1 Antibody Precios y disponibilidad
      MABE71 Anti-Histone Antibody, Pan, clone F152.C25.WJJ Precios y disponibilidad
      AP182P Donkey Anti-Rabbit IgG Antibody, HRP conjugate, Species Adsorbed Precios y disponibilidad

      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies