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MAB335 Anti-Synaptobrevin Antibody, clone SP11

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MAB335
100 µL  
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      Descripción

      Replacement Information

      Ofertas especiales

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Po, FeELISA, WB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB335
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Synaptobrevin Antibody, clone SP11
      Alternate Names
      • VAMP
      References
      Product Information
      FormatPurified
      PresentationLiquid in 0.02 MPB and 0.25M NaCl, PH 7.6 with 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Synaptobrevin Antibody, clone SP11 is validated for use in ELISA, WB, IH(P) for the detection of Synaptobrevin.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry at 1:100-1:200

      Formalin fixed (fixed <4 weeks), paraffin embedded

      Frozen

      4% Paraformaldehyde

      Western blotting at 1:100-1:1,000.

      ELISA at 1:500

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenCrude synaptic immunoprecipitate (Human)
      CloneSP11
      HostMouse
      SpecificitySynaptobrevin [VAMP], 16kDa protein. Not reactive with bacterially expressed fusion protein.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Pig
      • Feline
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummarySynaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined.
      Gene Symbol
      • VAMP1
      • SYB1
      • Synaptobrevin-1
      • VAMP-1
      • DKFZp686H12131
      Non-Reactive Species
      • Rat
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P23763 # Involved in the targeting and/or fusion of transport vesicles to their target membrane.
      SIZE: 118 amino acids; 12902 Da
      SUBUNIT: Interacts with VAPA and VAPB.
      SUBCELLULAR LOCATION: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein (By similarity). & Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein.
      TISSUE SPECIFICITY: Nervous system, skeletal muscle and adipose tissue.
      SIMILARITY: SwissProt: P23763 ## Belongs to the synaptobrevin family. & Contains 1 v-SNARE coiled-coil homology domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 12 months.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MAB335 04053252468315

      Documentation

      Anti-Synaptobrevin Antibody, clone SP11 Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-Synaptobrevin Antibody, clone SP11 Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-SYNAPTOBREVIN [VAMP] MONOCLONAL ANTIBODY - 2378670 2378670
      MOUSE ANTI-SYNAPTOBREVIN [VAMP] - 3190954 3190954
      MOUSE ANTI-SYNAPTOBREVIN [VAMP] -2594378 2594378
      MOUSE ANTI-SYNAPTOBREVIN [VAMP] -2639350 2639350
      MOUSE ANTI-SYNAPTOBREVIN [VAMP] -2710254 2710254

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra.
      J E Galvin, T M Schuck, V M Lee, J Q Trojanowski, J E Galvin, T M Schuck, V M Lee, J Q Trojanowski
      Experimental neurology  168  347-55  2001

      Mostrar resumen
      11259122 11259122
      Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.
      Masliah, E, et al.
      Acta Neuropathol., 87: 135-42 (1994)  1993

      Mostrar resumen
      8171963 8171963
      Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex.
      Honer, WG; Hu, L; Davies, P
      Brain research  609  9-20  1992

      Mostrar resumen
      7685234 7685234

      Folleto

      Cargo
      Pathways and Biomarkers of Glutamatergic Synapse Flyer

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      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies