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MABN629 Anti-PPID Antibody, clone 6A5.1

This Anti-PPID Antibody, clone 6A5.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PPID.

Anti-PPID Antibody, clone 6A5.1: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: PPID, CYP40, CYPD UniProt Number: Q08752
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MABN629
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN629
      DescriptionAnti-PPID Antibody, clone 6A5.1
      Alternate Names
      • Peptidyl-prolyl cis-trans isomerase D
      • PPIase D
      • 40 kDa peptidyl-prolyl cis-trans isomerase
      • Cyclophilin-40
      • CYP-40
      • Cyclophilin-related protein
      • Rotamase D
      Background InformationPPIase D is one of a family peptidyl-prolyl-isomerases that help proteins fold during synthesis. Specifically, PPIases D catalyzes the cis-trans isomerization of proline imidic peptide bonds in peptides. Among the proteins assisted by PPIase D are HSP90, Estrogen receptor, cellular dynein, MYB, ILF2, XRCC6, GNB2L1 and RPS3. PPIase D also may regulate the interactions of other proteins including MYB and AHR. Through its protein folding exercise PPIase D becomes vital for proper protein transport and expression as well. Finally PPIase D is associated with assisting in the response to UV light induced apoptosis, cell viability in anaplastic lymphoma and hepatitis C virus replication and release. PPIase can be found localized in both the cytoplasm and the nucleus and is widely expressed. Note PPIase should not be confused with PPIF, or mitochondrial peptidyl-prolyl cis-trans isomerase F.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-PPID Antibody, clone 6A5.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of PPID.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected PPID in rat cerebellum tissue.
      Biological Information
      ImmunogenRecombinant protein corresponding to human PPID.
      Clone6A5.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PPID
      • CYP40
      • CYPD
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 42 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected PPID in 10 µg of HepG2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MABN629 04053252986543