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16-212 Anti-Myc Tag Antibody, clone 4A6, biotin conjugate

Detect Myc Tag using this Anti-Myc Tag Antibody, clone 4A6, biotin conjugate validated for use in WB.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Epitope Tags & General Use Research Sub-Category: Epitope Tags Gene Symbol: MYC, C-MYC, c-Myc UniProt Number: P01106
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16-212
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMBiotinMonoclonal Antibody
      Description
      Catalogue Number16-212
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Myc Tag Antibody, clone 4A6, biotin conjugate
      OverviewImmunogen: peptide corresponding to amino acids 410-420 (MEQKLISEEDL) of human Myc

      Specificity: Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.

      Species Cross-reactivity: Human, others not tested

      Ig Type: IgG

      Host: Mouse

      Molecular Weight: Varies depending upon the protein which is tagged
      References
      Product Information
      FormatBiotin
      PresentationPBS and 0.05% sodium azide before the addition of glycerol to 30%
      Quality LevelMQ100
      Applications
      ApplicationDetect Myc Tag using this Anti-Myc Tag Antibody, clone 4A6, biotin conjugate validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      Cloneclone 4A6
      HostMouse
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
      Gene Symbol
      • MYC
      • C-MYC
      • c-Myc
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01106 # Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
      SIZE: 439 amino acids; 48804 Da
      SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with JARID1A and JARID1B.
      SUBCELLULAR LOCATION: Nucleus.
      PTM: Phosphorylated by PRKDC.
      DISEASE: SwissProt: P01106 # Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. & A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.
      SIMILARITY: SwissProt: P01106 ## Contains 1 basic helix-loop-helix (bHLH) domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by western blot on Myc-tagged recombinant protein
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20°C
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      16-212 04053252623035

      Documentation

      Anti-Myc Tag Antibody, clone 4A6, biotin conjugate Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-Myc Tag Antibody, clone 4A6, biotin conjugate Certificados de análisis

      CargoNúmero de lote
      Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - 2361471 2361471
      Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - 2398910 2398910
      Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - DAM1408780 DAM1408780
      Anti-Myc Tag, clone 4A6, biotin conjugate - 26847 26847
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3144495 3144495
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3485011 3485011
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3671808 3671808
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3677763 3677763
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3713397 3713397
      Anti-Myc Tag, clone 4A6, biotin conjugate - 3792890 3792890
      Show more

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      Alternative Format

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      Familias de productos

      Myc Tag Antibodies

      Millipore’s Anti-myc antibodies demonstrate specificity against the myc-tag. See below for related products for myc. All Millipore antibodies are based on the expertise of Upstate & Chemicon.
      Más información >>

      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies