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ABC336 Anti-MORF4 Antibody

Anti-MORF4 Antibody is a highly specific rabbit polyclonal antibody, that targets Mortality factor 4 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-MORF4 Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional UniProt Number: Q9UBU8
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ABC336
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC336
      DescriptionAnti-MORF4 Antibody
      Alternate Names
      • MORF4 Antibody
      • MORF4
      • Mortality factor 4
      • Cellular senescence-related protein 1
      • SEN1
      Background InformationMortality factor 4 (MORF4) is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes typically by acetylation of nucleosomal histones H4 and H2A. NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, DNA repair and apoptosis. MORF4 is localized to the nucleus and has transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif. Additionally, MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
      References
      Product Information
      FormatAffinity Purified
      Control
      • K562 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-MORF4 Antibody is a highly specific rabbit polyclonal antibody, that targets Mortality factor 4 & has been tested in western blotting, IHC & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected MORF4 in human brain tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MORF4 in HepG2 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human MORF4.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~33 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in K562 cell lysate

      Western Blotting Analysis: 2 µg/mL of this antibody detected MORF4 in 15 µg of K562 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      ABC336 04053252901355